Does Codeine Show Up on a Drug Test?
Evidence-based answer reviewed against SAMHSA cutoffs and FDA assay documentation · Updated August 2026
Quick answer: Yes. Codeine is one of the core analytes on standard 5-, 10-, and 12-panel drug tests. Covered by the standard opiate strip: 2,000 ng/mL morphine/codeine.
Which panels screen for it
| Panel | Codeine status |
|---|---|
| 5-Panel | ✅ Included |
| 10-Panel | ✅ Included |
| 12-Panel | ✅ Included |
| DOT 5-panel (safety-sensitive) | ✅ Included |
The details that matter
Lean's codeine lands squarely on the classic opiate panel — this is one street drug standard testing catches without any expansion.
Promethazine itself isn't screened, but it can flag old-generation amphetamine screens as a false positive; confirmation sorts it out.
Prescription codeine (codeine-acetaminophen tablets, cough syrup) verifies via MRO like any opioid script.
If it IS detected, how long does it last?
| Test type | Typical Codeine detection window |
|---|---|
| Urine | any: 1–3 days (codeine) |
| Saliva (Mouth Swab) | any: 1–2 days |
| Hair Follicles | up to 90 days |
| Blood | any: ~12–24 hours |
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Does Promethazine Show up on Drug Test?
Yes — Codeine sits on standard 5/10/12-panel screens. Prescription? Declare it for MRO verification.
Will Promethazine Show up in a Drug Test?
Yes — Codeine sits on standard 5/10/12-panel screens. Prescription? Declare it for MRO verification.
How accurate are drug tests?
Lab-based immunoassay screens agree with confirmation testing ~97% of the time; confirmed GC–MS results are considered definitive. Home kits trade legal defensibility for convenience.
Do prescriptions count against me?
No — verified prescriptions report as negative through the Medical Review Officer. Declare medications at collection and answer the follow-up call.
Sources & further reading
- SAMHSA — Mandatory Guidelines for Federal Workplace Drug Testing Programs (cutoffs, MRO process)
- DOT — 49 CFR Part 40 procedures for transportation workplace testing
- Brahm NC et al., Mayo Clinic Proceedings 2008;83(1):66–76 — false-positive cross-reactivity reference
- FDA — drug-of-abuse test device labeling (detection window conventions)