What Is a 10-Panel Drug Test? Drugs Detected, Cost & Accuracy?

Evidence-based answer reviewed against SAMHSA cutoffs and FDA assay documentation · Updated August 2026

Quick answer: A 10-panel drug test screens for the following drug classes — see the full list below with cutoffs.

Complete drug list

Standard configuration with typical urine immunoassay cutoffs:

Drug classTypical urine cutoff
THC50 / 15
Cocaine150 / 100
Opiates incl. heroin2000 / 2000
Amphetamines500 / 250
PCP25 / 25
Barbiturates~250–300
Benzodiazepines~300 / 200
Methadone~300 / EDDP
MDMA500 / 250
Propoxyphene/propoxyphene (legacy)~300

Who uses this panel

The default 'general workforce' panel for many non-DOT employers — everything DOT tests plus depressants and ecstasy.

What it does NOT catch

Blind spots: Oxycodone/hydrocodone slots vary; buprenorphine, fentanyl, kratom, shrooms, LSD absent. Absence from the strip means no testing occurs — specialty panels extend coverage when programs need it.

Cost & logistics

Cash-pay pricing for a 10-panel typically runs $30–$100 depending on lab network and turnaround. Results release in 1–2 business days for negatives; positives add confirmation and MRO review time. Home versions of most cup sizes sell for $15–$45 at pharmacies.

Certified labs nationwide · Results in 1–2 days

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Medical disclaimer: DrugPanels provides educational information about laboratory drug testing and does not offer medical advice, diagnosis, or treatment. Detection windows are population ranges — individual results vary with metabolism, dose, frequency and health status. Never stop prescribed medication to pass a test without talking to your prescriber. Affiliate disclosure: some links on this page are affiliate links; if you order through them we may earn a commission at no additional cost to you.

People also ask

How accurate are drug tests?

Lab-based immunoassay screens agree with confirmation testing ~97% of the time; confirmed GC–MS results are considered definitive. Home kits trade legal defensibility for convenience.

Do prescriptions count against me?

No — verified prescriptions report as negative through the Medical Review Officer. Declare medications at collection and answer the follow-up call.

Related guides

5 Panel Drug Test

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10 Panel Drug Test

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12 Panel Drug Test

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Sources & further reading

  • SAMHSA — Mandatory Guidelines for Federal Workplace Drug Testing Programs (cutoffs, MRO process)
  • DOT — 49 CFR Part 40 procedures for transportation workplace testing
  • Brahm NC et al., Mayo Clinic Proceedings 2008;83(1):66–76 — false-positive cross-reactivity reference
  • FDA — drug-of-abuse test device labeling (detection window conventions)